Explorer.exe error in Vista

[TheZomi]

I often got the following error when I click on the Start button and try to open some program or control panel in Windows Vista.

Problem signature
Problem Event Name: APPCRASH
Application Name: Explorer.EXE
Application Version: 6.0.6000.16386
Application Timestamp: 4549b091
Fault Module Name: Explorer.EXE
Fault Module Version: 6.0.6000.16386
Fault Module Timestamp: 4549b091
Exception Code: c0000005
Exception Offset: 00032791
OS Version: 6.0.6000.2.0.0.256.1
Locale ID: 1033
Additional Information 1: 8d13
Additional Information 2: cdca9b1d21d12b77d84f02df48e34311
Additional Information 3: 8d13
Additional Information 4: cdca9b1d21d12b77d84f02df48e34311

I search several forums for the solution but they said this problem occurs due to ZipGenius program of McAfee Antivirus. I did not used any of these programs.

Please tell me how to solve this?